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EXACT

Collaborative annotation of images at any scale — whole slide histopathology, MRI volumes, z-stacks, and more.

MIT license PyPI Paper

  • 🚀 Quick Start

    Get EXACT running with Docker in minutes.

    → Installation

  • ✏️ Annotation Workflow

    Draw, verify, and export annotations on images of any size.

    → Workflow guide

  • 🖼️ Image Formats

    WSI, z-stacks, NIfTI MPR, CZI, iSyntax — and extensible for more.

    → Supported formats

  • 📡 REST API

    Full OpenAPI reference and Python client examples.

    → API reference

  • 🧩 Plugin System

    Connect your trained models to EXACT via EXACT-Sync.

    → Plugin guide

  • 🔧 Developer Guide

    Architecture, custom image formats, frontend internals.

    → Architecture

Why EXACT?
Scale Multi-gigapixel WSI, NIfTI volumes with axial / coronal / sagittal MPR, z-stacks
Collaboration Team-based access, concurrent annotation, two-pass verification
Algorithm integration Plugin system connects live deep-learning models — draw predictions, verify, retrain
Version control Full annotation history and dataset versioning
REST API Complete programmatic access; Python client via EXACT-Sync
Offline sync Bi-directional sync with SlideRunner

Citation

@Article{marzahl2021exact,
  title   = {EXACT: a collaboration toolset for algorithm-aided annotation
             of images with annotation version control},
  author  = {Marzahl, Christian and Aubreville, Marc and Bertram, Christof A.
             and Maier, Jennifer and Bergler, Christian and Kr{\"o}ger,
             Christine and Voigt, J{\"o}rn and Breininger, Katharina and
             Klopfleisch, Robert and Maier, Andreas},
  journal = {Scientific Reports},
  year    = {2021},
  volume  = {11},
  pages   = {4343},
  doi     = {10.1038/s41598-021-83827-4}
}

Video Tutorials

Description Video
EXACT installation with Docker (en)
EXACT First steps (en)
EXACT Product and Annotation type definition (en)
Study and annotation modes (en) · Code
AnnotationMaps (en) · Code
DensityMaps (en) · Code
Cluster annotations (en) · Code
Annotation Versioning (en)
Inference (en) · Code
Segmentation (en) · Code
EXACT Media Files (en)
Datasets (en)
Image sets and uploads (en)
Viewer and plugin functions (en)
Image registration (en)
Sync with SlideRunner (en)
Advanced polygon operations (de)
REST API example pip install EXACT-Sync · Code · Notebooks · Postman